杰西卡·H. 托马斯,Ph值.D.
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传记
My studies focus on biomedical research, specifically how cells fuse in the developing nematode Caenorhabditis 线虫 (C. 线虫).
Cell-cell fusion is a developmental process during which individual cells merge by fusing their plasma membranes and forming a shared cytoplasm. The result is a multinucleated cell, which is also known as a syncytium. Cell fusion is an essential process for fertilization to occur and to create, 模式, and maintain tissues such as skeletal muscle, 骨, 胎盘, and the vertebrate eye lens. 除了, cell fusion is shown to be involved in insect wound healing and fungal colony formation as well as cancer and stem cell biology (Shinn-托马斯。 and Mohler, 2011). The only known proteins not of viral origin, EFF-1 and AFF-1 (a.k.a C. 线虫 fusion family (ceFF)), responsible for fusing cells have been identified in C. 线虫 (Mohler等人., 2002; Sapir et al., 2007). I investigate the 分子 and 细胞 regulation of EFF-1 and AFF-1 in cells fated to fuse in C. 线虫 using a variety of genetic, 分子, 细胞, and microscopy techniques in order to further elucidate a common cell-cell fusion mechanism.
Opportunities for Student 研究 and Collaboration
研究 with me usually involves working on some aspect of examining how cells fuse in C. 线虫 (a.k.a. “蠕虫”). 然而, I am also interested in and welcoming of collaborative research with other professors and their research. After we discuss your interests, 我的兴趣, and the unanswered questions in which we are both interested, we will pick a problem for you to tackle, which very well may (and hopefully) lead to additional interesting questions. Please visit the link to my lab web site to learn more about ongoing and potential research projects in my lab: http://jessicathomasbio.weebly.com/
教育
B.S. in Biology, Union College
Ph.D. in Biomedical Science-Genetics and Developmental Biology, University of Connecticut Health Center
研究
Please visit my lab website for publications and presentations: http://jessicathomasbio.weebly.com/
课程
BIO 211 General Biology I (lab)
BIO 232 研究 Methods II
BIO 321 Genetics (lecture and lab)
BIO 322 Developmental Biology (lecture and lab)
BIO 420 Special Topics in Biology
BIO/ANB 450 Senior 研究
BIO 453 Molecular Biology (lecture and lab)
BIO/ANB 495 Senior Seminar
UCC 101 FirstYear Seminar
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